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However, our understanding of how NETs contribute to the development of CF-associated proteolytic lesions and the decline of lung function in CF has been hampered, until recently, by the lack of an animal model that reproduces all of the features of the human disease.
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However, studies of the lymphatic system have been hampered until recently by the lack of markers that definitively distinguish blood from lymphatic vessels and a paucity of knowledge about growth factors specific to lymphatic endothelial cells.
However, the development of a similar approach for neurosteroids has been hampered by the limited knowledge that, until recently, has surrounded the identity of the amino acid residues contributing to the neurosteroid binding pocket.
McDonnell, 55, said the department tries to recruit in the black, Latino and Cambodian communities but until recently has been hampered by a hiring freeze.
However, timely analysis using second-generation platforms such as Illumina and Ion Torrent has been hampered by the need to wait until a sufficient read length has been achieved for diagnostic pathogen identification, as sequence reads for these platforms are generated in parallel and not in series.
Until recently, this effort has been hampered by the challenges of clinical trial design given the low prevalence of disease, clinical heterogeneity, relapsing-remitting course, and lack of well-established endpoints [ 2- 4].
Lamoriello says Clemmensen can provide relief for Brodeur until Corey Schwab, 33, who has been hampered by a groin injury all season, can return, perhaps by the playoffs.
Until now, military development in space has been hampered by a 1969 law limiting space exploration to "peaceful uses".
Until now RF-EMF risk assessment has been hampered by the lack of reliable exposure assessment methods.
Until now, detailed characterization of the SfaXII protein has been hampered by difficulties in obtaining large quantities of soluble protein.
Until recently the uptake of FM in LMICs has been hampered by the high cost, complexity and poor user-acceptance of conventional FM systems.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com