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Although the exact function is still unknown, slr0144 has been suggested to encode a PSII-associated protein [ 16], and slr0373 forms an operon with slr0374 which has been found responsive to various environmental stresses [ 17].
We used phosphorylation of the ribosomal protein S6 as a readout for mTORC1 activation, as it has been found responsive to mTORC1 inhibition using immunohistochemistry 7. We found that mTORC1 is constitutively active in neurons of the ventral horns and a subpopulation of neurons in the intermediate zone, with little activity seen in glial cells in the uninjured spinal cord.
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Hepcidin expression has been found responsive in different fish species when challenged with lipopolysaccharides (Hirono et al. 2005) and pathogenic bacteria (Wang et al. 2009).
Serum lysozyme activity has been found to be responsive to dietary fucoidan (El-Boshy et al. 2014; Prabu et al. 2016).
The SWLS has adequate internal consistency and validity in research on aged populations and has been found to be responsive to physical activity in older adults [ 17, 27].
The enolase protein has been found to be responsive to several biotic [ 22] and abiotic stresses [ 23, 24] in different plant species.
In ruminants, milk fat has been found to be especially responsive to dietary manipulation [ 4], providing an avenue to modify the fatty acid (FA) profile of milk fat in favor of health promoting isomers, and also a great model for scientists to study the mechanisms of mammary lipogenesis.
Although the low CD74 expression in the LN18 cells most likely account for the unresponsiveness to exogeneous MIF, a different glioma cell line not expressing CD74 has been found to still be responsive to recombinant MIF - arguing for an alternative MIF receptor [ 34].
The electrodermal activity has been found to be more responsive to pleasant and unpleasant pictures than neutral ones, while the high arousing pictures evoked greater SCR amplitudes as compared to low arousing ones (Bernat et al. 2006).
The NRS has been found to be valid, reliable and responsive to change [ 31, 32].
Based on the results of this psychometric evaluation, the RLSQoL has been found to be reliable, valid and responsive to change in both TREAT RLS 1 and 2.
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