"has been first implicated" is grammatically correct.
You can use it to describe a situation where someone or something is associated with or suggested as being responsible for an event or situation. For example: "The suspect has been first implicated in the robbery."
Such variants in the BRCA1 3'UTR have recently been identified and were first implicated in breast and ovarian cancer susceptibility in high-risk families [ 16].
The majority of studies have focused on the S180L polymorphism that was first implicated in a Caucasian cohort with invasive pneumococcal disease.
First, Cas4 has been strongly implicated in the acquisition stage and it has been shown to generate 5′-overhangs on DNA fragments compatible with a spacer uptake mechanism [ 23, 40].
It was the first time Najib has been directly implicated in the investigation into 1MDB, which is weighed down by an estimated $11bn of debt.
This is the first time senescence has been directly implicated in the progression of intestinal cancer and allows us to identify a distinct difference in the evolution of serrated CRCs compared to APC-mutated CRCs.
To our knowledge, this is the first time that CXCL8 has been directly implicated in the angiogenic process of the human bone marrow system, and this may have future clinical applications.
The ozone hole over Antarctica has been implicated for the first time in harm to animal life.
The first has been implicated in the accumulation of glycogen in stationary growth phase [28].
Cytosolic Ca2+ has been implicated as a second messenger of proapoptosis involved in both triggering apoptosis and regulating caspases or calpains [32] [34].
In adults, ADH7 has been implicated in the first-pass metabolism of ethanol taking place in the gastroesophageal tissues, before the ethanol is delivered to the liver via the portal vein (Hurley et al. 2002 ).
