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Thirdly, mice in which the GR has been disrupted using a lentivirus-based strategy in the central nucleus of the amygdala (CeA), did not display a decrease in innate fear but showed deficits in fear conditioning [48] [50].
Illustrating the importance of these methodological issues, the lncRNA Fendrr has been disrupted using 2 independent strategies; although both methods resulted in a lethal phenotype, Fendrr deletion led to delayed development of the lungs (Sauvageau et al. 2013), while multisystem defects were observed after insertion of a transcriptional termination signal (Grote et al. 2013).
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In mice, several thousand genes have been disrupted using homologous recombination.
In DNA viruses, contact sites have been disrupted using both peptides and small molecules, leading to ablation of virus replication.
Even if JI's network has been disrupted, they may be using personal contacts to orchestrate attacks.
"We opened this report by asking whether democracy has been disrupted by the use of data analytics and new technologies.
In this study, we have explored this hypothesis using mice in which the PKC δ gene has been disrupted (δKO).
Education has been disrupted.
Family life has been disrupted.
THE disruptor has been disrupted.
The port has been disrupted.
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