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Until now, this device has been demonstrated to function well to repair human articular cartilage defects.
Although there are several ER-localized HSPs that can potentially chaperone PRRs, including calnexin, calreticulin, protein disulfide isomerase, gp96, thiol-oxidoreductase ERp57, and BiP, to date only gp96 has been demonstrated to function in PRR-folding [44].
For instance, within the NCBI database, the highest similarity protein to L-alanine amidase BA4073 identified by IVIAT is the B. anthracis specific gamma phage lysin, PlyG, with 82% identity over the full length of both proteins, and PlyG has been demonstrated to function as a species-specific B. anthracis lysin [18].
Although the tetracycline transcriptional activator system [ 48] has been demonstrated to function in transgenic pigs [ 49, 50], recombinases have not.
We chose the minimal CMV promoter (mCMV), which has been demonstrated to function in various mammalian cells.
Recently, GILZ has been demonstrated to function as an endogenous inhibitor of chronic inflammation in a murine model of RA [ 31].
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Many other functionalities have been demonstrated to function as unnatural internucleoside linkages, including ethers, esters, sulfonates, amines, phosphonates, and amides (Schneider and Benner, 1990a; Li et al., 2002; Bean et al., 2006; Cleaves and Bada, 2012).
Many adamantane derivatives have been demonstrated to function as 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors.
We examine the functions that have been determined for several spirochetal OMPs including those that have been demonstrated to function as adhesins, porins or to have roles in complement resistance.
Permeable Pavement Structures (PPS), designed to improve drainage of urban paved areas, have been demonstrated to function as hydrocarbon traps with 98.7% efficiency and as powerful in-situ aerobic bioreactors.
Indoles and cresols have been demonstrated to function as oviposition attractants for Culex mosquitoes [16], [20], [21], [22], [23].
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