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It has also been suggested that these alternative isoforms might interact with unique ligands, but to date, no isoform-specific ligand has been convincingly identified.
The heritability of B cell chronic lymphocytic leukemia (CLL) is relatively high; however, no predisposing mutation has been convincingly identified.
However, no such factor has been convincingly identified, biochemically purified and tested to verify its role according to Koch's postulates for causation.
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The stem cells responsible for the posterior addition of axial mesodermal tissues have been convincingly identified by molecular signatures [ 20].
However, the identification of causal functional DNA polymorphisms underlying QTL has remained problematic, with such variations having been convincingly identified for no more than 9 QTL [ 2].
So far, the genes IRF5 (Interferon regulatory factor-5) and STAT4 (Signal transducer and activator of transcription 4) have been convincingly identified and replicated in several studies as susceptibility factors of primary SS independent of the presence of autoantibodies.
It is also a very effective gene finder for eukaryotic genomes [54], and its accuracy to identify unannotated genes has been convincingly demonstrated by laboratory experiments [53].
Indeed, miRNA profiling has been convincingly demonstrated to classify tumor and non-tumor samples more effectively than gene expression profiling and, more importantly, identifying breast cancer subtypes (Blenkiron et al. 2007; Iorio et al. 2005; Lu et al. 2005).
— and no one else has been convincingly tied to the murder.
The link between these pathologies and different aspects of work organization has been convincingly proven.
The anti-suicidal effect has been convincingly demonstrated in bipolar as well as in unipolar patients.
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CEO of Professional Science Editing for Scientists @ prosciediting.com