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In the intestinal PP, a third subset of CD11c+ DCs distinct from lymphoid and myeloid phenotypes, has been characterized which does not express either high levels of CD11b or CD8α molecules and are thus defined as double negative DCs (CD11b−, CD8α−) [40], [40].
To date, only a single flax β-galactosidase (LuBGAL1) has been characterized, which has an important role in the development of cell walls of phloem fibres [ 8].
Additionally, an N-acylethanolamine-specific phospholipase D (NAPEPLD, Q6IQ20) has been characterized, which appears to have a role in the generation of endocannabinoids/endovanilloids, including anandamide 246.
To date, only one class III lanthipeptide protease has been characterized, which cleaves a similar leader peptide as the predicted informatipeptin leader peptide.
a bifunctional delta-fatty acyl acetylenase/desaturase has been characterized which displays a redundant functionality, being able to introduce a Delta6cis-double bond into 9,12, 15 -C18-polyenoic , 15 -C18-polyenoic , 15 -C18-polyenoic-double bond to acidstas-triple bond [ 50].
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Thirty radioisotopes have been characterized, which range in mass number from 209 to 238.
In mammals, two adenosine deaminases that act on RNA (ADARs) have been characterized, which mediate all of the currently known A-to-I editing events [1].
Numerous types of modifications have been characterized, which are generally specific for a given type of RNA such as the CCA addition found in tRNAs.
Several bacterial proteases that degrade membrane proteins have been characterized which provides insight into the approximate degradation timescale (Dalbey et al., 2011).
Since AMA failed to be clearly related to the etiopathogenesis of PBC it is encouraging that several new antibodies have been characterized, which might be associated with disease stage [ 48] or with new concepts for the etiopathogenesis of PBC [ 49].
While several murine models have been characterized which mutate and/or toggle cyclin D1 expression, to date no genetic systems had been generated which assess cyclin D1b function under the endogenous promoter in vivo.
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