Sentence examples for has been a substantial issue from inspiring English sources

The assessment of comparable dosimetry for animals in different life stages has been a substantial issue in discussions of the analysis of these data.

Nevertheless, there has been a substantial amount of debate on this issue (see Haliwell et al, 1994).

"We can confirm there has been a substantial burglary at Ramsbury Manor," said a spokesperson in a statement issued on behalf of Mr Hyams.

This has been a substantial success.

Run support has been an issue.

But funding has been an issue.

Price could have been an issue.

Since there have been growing numbers of non-inferiority trials published in recent years, this may be a substantial issue.

"But there's a substantial issue about my client's mental state".

This is a substantial issue requiring attention.

When assessing imported malaria cases, underreporting is a substantial issue.