Nor did they mention that while getting alarmingly closer, Iran does not yet have an actual weapon — reportedly, a computer worm that appears to have been worked on by Israel and the United States is believed to have been a significant setback.
Despite the setbacks of the clinical trials in the 1960s, there has been a recent and significant revival of interest in vaccines against RSV, with several promising candidates undergoing evaluation.
BUSINESS DAY, PAGE C1 Pornography Sites Shuttered Business at Web sites that offer child pornography generated by Web cameras has been dealt a significant setback.
A17 Pornography Sites Shuttered The business for Web sites that offer child pornography generated by Web cameras has been dealt a significant setback as some of the most trafficked sites that directed potential customers to minors' online Webcams have shut down.
For lesser sides, it might have been a crushing setback.
"There have been a million setbacks".
Chances are they have been waiting patiently since you re-scheduled and if you miss the moment, or forget (or seem to have forgotten), it will be a significant setback to your progress, and a reminder of less affectionate days gone by.
The previous year had been an even bigger setback.
For the Muslims, the battle was a significant setback: although they had been close to routing the Meccans a second time, their breach of Muhammad's orders in favor of collecting Meccan spoils reaped severe consequences.
It is a significant setback for Mr. Obama, who has made Asia a centerpiece of his foreign policy.
