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Wolfowitz has been a major architect of President Bush's Iraq policy and, within the Administration, its most passionate and compelling advocate.
General Alexander has been a major architect of the American strategy on this issue, but until Tuesday he almost always talked about it in defensive terms.
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Abdullah has been a major disappointment.
The New York Stock Exchange has been a major hindrance.
"There has been a major information gap.
He was very critical of recent restorations of medieval churches, which had been a major occupation of architects during the previous 20 years, and was particularly caustic about the removal of whitewash from the interior of churches, and the damage thus caused to the underlying stonework.
It could have been a major pain.
He was a major architect of the new health care program and the cigarette tax increase, and he has called for gun control and hate crimes legislation.
Chapelain was a major architect of Classicism in France.
The company said he was a major architect for developing and executing Yum's founding strategies, structure and culture.
He has been widely vilified as a major architect of the Vietnam War, which cost more than 58,000 American lives and, Mr. McNamara says, the lives of 3.4 million Vietnamese.
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