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There has been a considerable debate, however, regarding the number issue, i.e., whether HbA1c should be expressed in percentage units related to the DCCT study or mmol/mol related to the IFCC method.
Since the application of excimer laser technology for the correction of eye's simple refractive errors (i.e. defocus and astigmatism), there has been a considerable debate concerning the visual impact of correcting the higher order monochromatic aberrations of the eye (e.g. spherical aberration, coma and secondary astigmatism), which also degrade retinal image quality [ 1- 4].
There has been a considerable debate regarding the most appropriate form of supervised exercise for chronic low back pain, however, at present there is no evidence to inform this debate because there has never been a direct comparison of the two approaches.
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The cause of this political impotence in Norway has been a subject of considerable debate.
How to approach this issue has been a matter of considerable debate in an administration that has long been riven ideologically on the issue of the United Nations.
Among close observers of the Sinaloa cartel, the extent of Chapo Guzman's own wealth has been a subject of considerable debate.
How to undermine Mr. Milosevic, who has been indicted by the international war crimes tribunal in The Hague, while unifying the the squabbling factions of the opposition, has been a subject of considerable debate within the State Department.
Whether reduction of this sort is acceptable has been a matter of considerable debate.
But what actually happens inside the brain has been a source of considerable debate.
This form of inner awareness has been a topic of considerable debate, centuries after the issue arose with Locke's notion of self-consciousness on the heels of Descartes' sense of consciousness (conscience, co-knowledge).
The selective pressure that shaped the original lemuriform toothcomb has been a topic of considerable debate since the 1970s.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com