This problem has become significant and ubiquitous in distributed systems as the Internet rapidly grows as a mainstream service platform and requires increasing automatic coordination and cooperation between services at two ends.
The Information Technology Association of America, a trade group, said last week that it would help create the Coalition on Online Identity Theft, composed of Internet retailers and security companies allied against what has become a significant problem both online and off.
Back to the top In the universal credit white paper (pdf), the government argues: "Welfare dependency has become a significant problem in Britain with a huge social and economic cost".
This means it pays higher rates, but it is also not running into what has become a significant problem for political advertisers this year: getting bumped by someone offering to pay a higher price.
Drug resistance has become a significant problem in some helminth populations, and this has promoted interest in the development of immunoprophylactic strategies.
Heavy metal contamination has become a significant problem in several community and agricultural areas over the years due to the application of commercial agrochemicals on agricultural production (Vodela et al. 1997; Rattan et al. 2005).
However, resistance to antitubulin drugs has become a significant problem due to P-glycoprotein overexpression and, perhaps, to mutations in genes encoding the tubulin subunits, changes in tubulin isotype composition of MTs, altered expression or binding of MT-regulatory proteins including Tau, mutations in or reduced levels of γ-actin, and/or a reduced apoptotic response [3], [6].
