More recently, mathematical models in conjuction with advances in experimental techniques have allowed estimates of CTL killing rates in vivo [9] [14].
This has allowed exposure estimates to take into consideration how an animal uses an area as well as the proportion of contaminated sites that animals may use.
However, this approach has allowed unbiased estimates of seroprevelance from a design that was not intended for studying these diseases, allowing maximum information to be extracted from such a survey and the banked material and providing robust estimates for these infections.
This database has allowed cumulative estimates to be made of the cancer risks conferred by mutations in BRCA1 [ 3] and BRCA2 [ 4, 5].
The methodology has allowed us to estimate the utility of a very large number of combinations of side effects and disease states within MBC.
Recently, progress in molecular and population genetic techniques has allowed us to estimate the evolutionary and demographic histories of recently diverged populations or species reliably.
The deterministic approach has allowed us to estimate different parameters of the model and reproduce the switch-like behaviour of the QS network.
This joint study has allowed us to estimate the impact of heat exposure on an elderly population in urban locations, and our findings highlight the role of high nighttime temperatures and the duration of heat.
