A multispan viral membrane protein encoded by the bmrf2 open reading frame has additionally been implicated in attachment.
I/R in the intestine has additionally been implicated in the pathogenesis of necrotizing enterocolitis in preterm delivered neonates.
We note that Reck has additionally been implicated in endocytic trafficking (Miki et al., 2007), focal adhesion formation and cell polarity (Morioka et al., 2009) processes that may affect Wnt/β-catenin signal transduction (Fonar and Frank, 2011; Feng and Gao, 2014).
Mcl-1 [7] and, to a lesser extent, A1 [8] have been shown to be important for maintaining neutrophil survival, and have additionally been implicated in signalling extended neutrophil lifespan in response to a variety of stimuli including cytokines [9], elevated cAMP [10] and hypoxia [11], [12].
However, besides preclinical efficacy, these treatment opportunities have yet to demonstrate clinical efficacy and have additionally been implicated in the development of adverse musculoskeletal events [ 2].
Members of the FGFR family of receptor tyrosine kinases are of tremendous significance in many aspects of normal development and, additionally, have been implicated in a variety of human cancers, such as FGFR4 with regards to prostate cancer [8], [9], [10].
63, 64 The purinergic receptor P2Y family also stimulates adenylyl cyclase activation and cAMP production 65 and, additionally, have been implicated in white adipocyte physiology, including leptin secretion and lipolysis.
Additionally, HOXA4 has also been implicated in the regulation of microRNA genes during monocyte differentiation, suggesting microRNAs as one mechanism for HOX gene regulation of cell-type specific effects [ 39].
Additionally, Pex3 has been implicated in peroxisome segregation in S. cerevisiae (Munck et al, 2009), and a Pex3-like protein has been implicated in this process in Yarrowia lipolytica (Chang et al, 2009).
Additionally, ghrelin has been implicated in a variety of other physiologic processes, including cardiovascular function, learning, memory, reward behavior, and addiction.
Additionally, TRAX has been implicated to function as a localization factor for translin.
