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These data suggest that either AMPK plays a larger role, or has additional mechanisms of action, that are required for cell survival in colon cancer cells but not in non-transformed colon epithelial cells.
Nevertheless, aspirin has additional mechanisms that may underlie benefits in neuropsychiatric illness.
For example, while both F. tularensis SchuS4 ΔpyrF and LVS ΔpyrF strains are deficient for intramacrophage growth, LVS ΔpyrF induces significantly higher levels of TNF-α than wild-type LVS in exposed macrophages whereas SchuS4 ΔpyrF does not, suggesting it has additional mechanisms for attenuating cytokine expression in macrophages compared to LVS [ 12].
Compared to the decentralised system of recruitment, the re-instated central recruitment of health workers was perceived by a large majority of the study participants to be more effective in balancing health worker distribution across districts as it has additional mechanisms for ensuring that health workers are distributed relative to the needs of the districts.
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Consequently, all large organisms (even plants) have additional mechanisms for moving fluids to bring metabolites close to the cells.
Specialist parasites, many of which are obligates, tend to have additional mechanisms to detect their specific host plants.
Because the importance of reliable repetitive firing in motoneurons, it is possible that they have additional mechanisms to safeguard firing properties.
Despites these similarities, 4-oxo-4-HPR seems to have additional mechanisms of action compared to the parent drug, also suggested by its ability to be effective in 4-HPR resistant cells [12].
These results demonstrate that ortho-hydroquinone-PCBs have additional mechanisms for radical formation as compared to para-hydroquinone PCBs.
Because of this behavior, corals are expected to have additional mechanisms to protect themselves from potential pathogens.
These findings raise the possibility that maternal bonding may influence the prevalence of chronic pain mediated mainly by depression, while paternal bonding may have additional mechanisms.
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CEO of Professional Science Editing for Scientists @ prosciediting.com