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It must be injected, and it often has acute side effects, including debilitating fatigue.
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In sum, IA chemotherapy had few and low-grade acute side effects.
Severe acute side effects have also been associated with consequential late effects in normal tissue (Dörr and Hendry, 2001).
Thus, kinase inhibitors especially those that have a broad target spectrum should be carefully evaluated to prevent acute side effects.
In addition to the well-recognised acute side effects of chemotherapy the significance of late side effects have become increasingly appreciated.
Acute side effects were generally mild and 18 weeks after treatment, only four and five of the 126 men had persistent ⩾Grade 1 bowel or bladder side effects, respectively.
Thirteen (59%) withdrew, mostly because of acute side effects.
Acute side effects were assessed according to the Common Terminology Criteria for Adverse Events (CTCAE 4.0).
There are no known contraindications or acute side effects associated with the radiotracers.
There were no other acute side effects related to the administration of [11C]lapatinib.
Others say they did, but at an extreme cost, including acute side effects, crippling dependency or addiction.
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