Sentence examples for has a tolerability from inspiring English sources

In particular, it has a tolerability profile characteristics of NSAIDs, with gastrointestinal disturbances (pain, dyspepsia, nausea, and vomiting) being the most remarkable events.

With the exception of GI ulcers, the evidence indicates that lumiracoxib has a tolerability profile similar to nonselective NSAIDs: low risk of cardiovascular (CV) events and a low incidence of edema.

Sitagliptin, as monotherapy or as add-on therapy to other oral antihyperglycemic agents (AHAs), including metformin, a thiazolidinedione, and a sulfonylurea, has a tolerability profile generally similar to placebo [ 4- 13], although an increase in adverse experiences primarily due to an increase in hypoglycemia was observed when sitagliptin was added to ongoing therapy with a sulfonylurea [ 10].

Although eight subjects did not have a tolerability data recorded, their post procedure pain scores were of a low intensity and did not require termination of the procedure.

A single dose of palonosetron has been found to have a tolerability profile comparable to other drug class members; headache, constipation, and dizziness were the most commonly reported adverse events.

β blockers also significantly reduced deaths from cardiovascular disease as well as sudden deaths, while increasing ejection fraction by a mean of 4.1% and having a tolerability profile similar to the comparators (we postulated that drug discontinuation rates might be a surrogate endpoint reflecting tolerability of the individual β blockers) (table 2).

Raltegravir (RAL), an INI, has a favorable tolerability, safety, and metabolic profile, 76 and is well-tolerated as PEP.

Gabapentin has a good tolerability profile [154].

Despite its well-established efficacy and rapid onset of action, sumatriptan 6 mg SC injection has a suboptimal tolerability profile.

Effectiveness has been also tested concluding that buprenorphine is at least as effective as methadone and has a better tolerability profile in reducing illicit opioid when use in clinical practice [8, 12, 44].

A phase I study in healthy volunteers – the first study in the PROLONG-7FP program – confirmed that rVIIa-FP has a good tolerability profile in doses of up to 1,000 μg/kg and has demonstrated enhanced pharmacodynamic activity relative to rFVIIa.