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The fact that there is little evidence that underlying DNA has a substantial affect on histone modifications is perhaps unsurprising; patterns and distributions of histone modifications vary between cell types even when from the same genetic background.
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Surface charge of NDs has shown to have a substantial affect on protein adsorption60.
None of the constructs had a substantial affect on the growth of the host strain.
Therefore, we think it unlikely that response bias has had a substantial affect on the results, although it is possible that there were differences in the level of deprivation between responders and non-responders.
Disability has a substantial impact on the quality of life of patients and affects daily living [ 1].
Chronic migraine affects up to 2%% of the general population and has a substantial impact on sufferers.
Although the multiplication of bacteriophages (phages) has a substantial impact on the biosphere, comparatively little is known about how the external environment affects phage production.
These issues have a substantial impact upon oncology practice, affecting patient's well being and medical workload.
But the deadlock in Washington goes beyond creating uncertainty: it is having a substantial impact on taxes and government spending, which directly affect the economy.
These conditions affect reproductive aged women and can have a substantial impact on quality of life, with resultant impairment of education/work.
The report also detailed the emotional toll for victims: one third said the fraud had a substantial impact on their health as well as their financial well-being, while 167 were affected so badly they had to receive medical treatment.
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CEO of Professional Science Editing for Scientists @ prosciediting.com