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Historically, eQTLs have been classified into cis and trans (or distant), where cis eQTLs affect expression of a gene nearby and trans act at greater distances (usually on another chromosome) in a more indirect way, such as affecting the expression of a regulator that has a subsequent impact of the trans-controlled gene.
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This habitat shift had a subsequent impact on species distribution.
We could hypothesise that sunitinib treatment could interfere with the IGF-1 pathway, having a subsequent impact on insulin resistance.
Finally, while the primary objective of the study was to determine which agent was most effective at BP control based on achieving a physician-defined target BP, it is unknown if this type of goal has a subsequent clinically important impact on morbidity, mortality or downstream healthcare resource consumption.
The presence of residual active tumour following cancer therapy has a significant impact on subsequent management.
Since the first caesarean delivery has a major impact on subsequent pregnancies, optimising labour induction among nulliparous women is important.
Quality control of assemblies is essential because the quality of the assembled contigs has a direct impact on subsequent analyses.
More precisely in this context dispatching an ambulance in order to serve a specific emergency request has a direct impact on subsequent requests that might appear in the same region or close by.
Although it is undoubted that the instructional approach used to introduce novel clinical technical skills to learners has a decisive impact on subsequent skills performance, as yet, little is known about differential effects of varying instructional methods.
Although it is undoubted that the instructional approach used to introduce novel clinical technical skills to learners also has a decisive impact on subsequent skills performance [ 9, 14], as yet, little is known about differential effects of varying instructional methods.
It is, therefore, possible that the duration of hypotension or hypoxia has a greater impact on subsequent graft viability than the duration from treatment withdrawal to cardiac arrest or cold perfusion.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com