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The top replicated gene, Hsd3b5 (involved in metabolism of steroid hormones), has a replication significance of p = 1.3×10−6.
The worst case takes place if M - 1 particles have zero replication factors and only the last stored particle in the FIFO has a replication factor = M.
Taken together, our present data indicate that Swi3 has a replication function that is independent of Cds1 activation.
IAV has a replication (RNA synthesis) strategy that amplifies their genomes many times per infection by using exclusively their own polymerase complex without any assistance from host RNA polymerases.
To determine if nbs1-2 has a replication defect, we tested whether it is sensitive to camptothecin, a DNA-damaging agent that causes DSBs at replication forks by preventing removal of topoisomerase I. Wild-type shows slower growth on medium containing 1 µM camptothecin than on medium that was mock-treated.
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Therefore, the C-catalyst has an replication advantage over the A-catalyst.
A previous study [ 18] has shown that in a replicator system with complex formation (as in the current system), parasites have a replication advantage over catalysts.
These are the effective provision of pre-school education (EPPE, later EPPSE) project (Sylva et al. 2004, 2010, 2014; Melhuish et al. 2008), which had a replication study in Northern Ireland (effective pre-school provision in Northern Ireland, EPPNI) and the National Evaluation of Sure Start impact study (NESS) (Belsky et al. 2008; Melhuish et al. 2010).
Many viruses have a replication strategy that involves double-stranded RNA (dsRNA).
The escape mutation in the epitope had a replication fitness cost, and another escape mutation outside the epitope was later acquired, allowing reversion of the first escape mutation and restoration of viral replication fitness [18], [23].
Taken together, these results suggest that PmNV and the nudiviruses might have a replication origin pattern which is distinct from the baculoviruses.
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