Sentence examples for has a reduced probability from inspiring English sources

This provides an explanation for the disappointing results associated with lumacaftor monotherapy in patients who are homozygous for the mutation [ 68] — if Phe508del-CFTR is expressed at the apical membrane, the chloride channel still has a (reduced) probability of being open [ 15, 39].

We conclude that the DNA-launched virus has a reduced probability of reversion mutations, thereby enhancing vaccine safety.

The disadvantage is that by deleting candidate locations at this early stage, the TALA has a reduced probability of detecting all target events.

If Phe508del-CFTR is expressed at the apical membrane — for example, following monotherapy with a CFTR corrector such as lumacaftor — it has been demonstrated that the chloride channel has a reduced probability of being open, operating as a class III gating CFTR mutation [ 15, 16].

Second-generation Turks in the French cities and in Stockholm have a reduced probability of achieving the highest levels of education when there are increased levels of parental support.

Those who achieve viral suppression and adhere to HAART have a reduced probability of transmitting HIV.

It is hardly surprising that horses not trained by the age of 18 months had a reduced probability for passing a recruitment race.

This model revealed that the fish ladder favoured fish migration upstream at a medium size (60 70 cm, max probability = 67.9 cm, Fig. 8A), with both smaller and larger fish having a reduced probability of using the fish ladder.

In the formation of a quasispecies, the population minimizes the mutational load by accumulating sequences that have a reduced probability to suffer from deleterious mutations [ 27, 28, 39, 40].

By calculating the number of changes away each of the candidate probe sequences identified in the first step is from the background, it is possible to identify those candidate probes which are sufficiently "distant" from the background and thus have a reduced probability of hybridizing with non-target genomic material present in the sample.

However, in the Rx and OTC group, for highly educated women the likelihood of reported medication use is greater among previously married women (OR 1.44, CI 1.20, 1.75) than their single counterparts, and in the Rx group women with a lower level of education who reported being previously married have a reduced probability of medication use (OR 0.57, CI 0.37, 0.88) than their single counterparts.