The Tyne, Tees, Swale, Aire, Don, and Trent rise in the Pennines, flow eastward, and have a long course to the North Sea.
The congenital bile duct cysts have a long course of disease, which may lead to increasing morbidity of several complications, including cholestatis, cholangiolithiasis, and even cholangiocarcinoma.
Chordoma has a long clinical course as it is typically slow growing; metastases tend to develop years after initial diagnosis.
AIH is a disease that often has a long subclinical course that leads to development of end-stage liver disease.
COPD has a long term course with chronic progression and is often underdiagnosed, and thus a community based integrated intervention at earlier stages or before development of COPD would have more impact than a hospital intervention among patients who have already developed moderately or severely symptomatic COPD.
If you developed a Candida infection because of having to take a long course of antibiotics (which is common), wait for the round of antibiotics to finish and clear your system.
Preferring the slow road — the byway, the back road — has a long tradition, of course.
The United States has a long history, of course, of putting aside concerns over human rights and democratic principles and supporting strongmen who can protect its strategic interests, like keeping the oil flowing or Communist sympathizers or Muslim extremists in check.
It is hard, but not impossible, to play without a member sponsor, but it has a long list of courses in the United States, Europe, Australia and Asia with which it has reciprocal privileges.
