Sentence examples for has a key functional from inspiring English sources

Recent data indicate LRRK2 is expressed in glial cells and that it has a key, functional role in orchestrating the inflammatory response of this cell population [31,32].

We hypothesized that lincRNA-p21 has a key functional role in UVB-induced apoptosis and/or cell cycle arrest in keratinocytes and loss of lincRNA-p21 function results in the evasion of apoptosis and/or cell cycle arrest.

For the murine form this loop is almost exclusively subject to high selection, which suggests that this part of the structure has a key functional role in these small peptides.

Both proteins seem to have a key functional role, since silencing of their genes can reverse the phenotype induced by the initial stimuli.

Both the HKD1 and HKD2 domains contained three highly conserved amino acids (6H, 8K and 13D), implying that these have a key functional importance within these domains.

The articular cartilage has a key structural and functional role in joint physiology and disease; therefore, a high number of in vitro models have been developed to study this specialized tissue in normal and pathological conditions.

Studies in both humans and primates have implicated a key functional role for the SMG in the transformation of sensory input into motor output, and the sensory guidance of behaviour (Binkofski & Buxbaum, 2012; Della-Maggiore, Malfait, Ostry, & Paus, 2004; Desmurget & Grafton, 2000; Desmurget et al., 2009; Rozzi, Ferrari, Bonini, Rizzolatti, & Fogassi, 2008; Rozzi et al., 2006).

As FLT3 signaling has a key role in important functional responses such as cell proliferation and survival, the effects of pacritinib on cell cycle and apoptosis were investigated.

Moreover, information from functional and structural genomics has a key role in the identification of novel antimicrobial targets.

BlackBerry has a key advantage.

Britain has a key aviation asset: Heathrow.