Sentence examples for has a fundamental function from inspiring English sources

Cross-presentation has a fundamental function in the induction of CD8+ T cell immunity and controls immune response against pathogens and immune tolerance to self-antigens.

Because deletion of tdp-1 perturbed the abundance of these transcripts, we hypothesized that TDP-1 has a fundamental function in the formation, or metabolism, of dsRNA.

Inappropriate hedgehog signalling has a fundamental function in an increasing number of malignancies, including childhood solid tumours such as medulloblastoma and RMS (Evangelista et al, 2006).

Nevertheless, the widespread and relatively strong expression of the gene in both species suggests that the protein has a fundamental function(s) in cells of many, if not all, tissues.

We set out to investigate whether NM1 has a fundamental function at class II promoters, contributing to the maintenance of a chromatin state required for Pol II transcription activation.

This could suggest that the C2-FerI-C2 motif functions as a single entity and may have a fundamental function shared between metazoan and protozoan putative ferlins.

CCL21, together with other homeostatic chemokines such as CXCL13, has been shown to have a fundamental function in the development of secondary lymphoid organs by interacting with CCR7 [ 4, 33].

The central cholinergic system has a fundamental role in normal cognitive function, and in diseases that exhibit cognitive dysfunction.

It is suggested that gene duplication has a fundamental role in diversifying gene function[ 45].

Zinc is one of these ions which has a fundamental role in the structure and function of numerous proteins, including metalloenzymes, transcription factors, and hormone receptors.

PIEZO2 has a fundamental role in sensory neuron mechanotransduction where it is necessary for mechanoreceptor function and touch4,5,8,9,47.