Since single cell measurements are performed by measuring the action of one cell at a time in a relatively isolated space, it is unlikely that the activated secretion of one platelet can have a downstream effect of activation on another one.
In Experiment 3, we tested whether the effect of abstract versus concrete framing on biological versus psychological attributions might have a downstream effect on the perceived efficacy of treatments for mental disorders.
Although it is believed that the jet reaches a universal self-similar state, there was early evidence that the inflow conditions can have a downstream effect on the development of the turbulent flow field.
However, our findings might indicate the relative failure of national regulations or national ethics committees to have a downstream effect on the practices of the research staff.
Thus, an IL-23-targeted therapy could potentially have a downstream effect on IL-17 production.
We therefore investigated whether CCN2 knock-down in CCD-1068SK fibroblasts would have a downstream effect on type I collagen gene expression.
Furthermore, acceptance criteria for entry to EIS vary, which will have a downstream effect on the number of new cases of clinically relevant psychoses received in each team.
Moreover, we documented the functional interactions of miR-205 and PTEN, which have a downstream effect on the regulation of the AKT pathway, explaining, at least in part, the inhibitory effects on Ishikawa cell apoptosis of enhancing miR-205 expression.
Elevated expression of a number of enzymes that can directly modulate the ECM has been reported, and recent data indicates that modulating the activity of these enzymes can have a downstream effect on fibrotic tissue remodeling.
Furthermore, an accumulation of nucleotide triphosphates due to lack of hydrolysis by NPP1 (Prosdocimo et al., 2009) could have a downstream effect on bone remodelling through purinergic signalling (Orriss et al., 2010).
