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The faster kinetics and greater magnitude of death in the NEMO-deficient cells, which has a disruption in both the first and second checkpoint, as compared to the IκBαSR-transfected cells, which has a disruption in the second checkpoint, indicated that disruption of the first checkpoint generates a more potent death signal.
Although EY7 has a disruption of the MATα locus, which prevents sporulation under normal conditions, sporulation can be induced in sporulation medium with 5 mM nicotinamide (St. Charles and Petes 2013).
The Mut+ phenotype grows on methanol at the wild-type rate and requires high feeding rates of methanol, the MutS phenotype has a disruption in the AOX1 gene and has a slower specific growth rate in methanol and the Mut- is unable to grow in methanol.
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During the blackout, the tenant never had a disruption.
"C.E.C. has never had a disruption of a contract in New Jersey or any other state, never missed a payroll, and never had a basis that necessitated disclosure of a nonissue," the company said.
Because of the relevance of the FA/BRCA pathway in the control of DNA repair, we first investigated whether CML cells had a disruption in this pathway.
One mutant cell line from the latter group was found to have a disruption of a small gene, DESR1 (later renamed Dph3), that is required for the biosynthesis of diphthamide [10], [18].
In the zebrafish embryo, this has been done through the identification and detailed characterization of genetic mutants which have a disruption of the retinal vasculature network [ 26].
Cats with FIC have been shown to have a disruption to the epithelial cytoarchitecture that increased diffusion and infiltration of urinary constituents [ 51, 52].
We explain to patients that there is always a small risk after primary breast augmentation that their implant may have a disruption.
The Parp-1-KO mice used in these studies have a disruption at the second exon of the Parp-1 gene (Wang et al., 1995).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com