COPD is a heterogeneous condition comprising many important clinical phenotypes that may have a different natural history or treatment response.
In general, poorly differentiated, high-grade carcinomas represent aggressive cancers that have a different natural history and response to treatment compared with well-differentiated, low-grade NETs.
Thus, the fact that maternal genes and developmental genes have a different natural nucleosome configuration at the promoter was already known.
One needs to be cautious in extrapolating from an experience in a tumour that has a different biology, natural history and response to therapy.
Compared to older generations, the Net Generation has a different but natural approach to technology, and they use digital media for knowledge construction and learning [ 9].
Every religion has a different explanation for natural disasters, but they can't all be true.
They experience strong truncation selection in the novel (hatchery) environment, which has a different fitness optimum from the natural environment.
To exemplify, the term adaptive capacity has a different meaning applied in social or natural sciences, thus an integrated understanding needed to be found.
