Sentence examples for has a critical function from inspiring English sources

Several experiments indicate that H3K27 methylation by E z) has a critical function in the establishment of transcriptional repression of PRC2 target genes.

Knocking out the Oct-4 gene in mice causes early lethality due to the lack of ICM formation, indicating that Oct-4 has a critical function for self-renewal of ES cells [25].

Although not the exclusive pathway, CARD9 also has a critical function in NOD2-mediated activation of the kinases p38 and Jnk, required for the production of pro-inflammatory cytokines in innate immune responses to intracellular pathogens[8].

The LsRXR has a critical function during reproduction in female salmon louse.

ProS has a critical function in regulating coagulation in several critical steps [ 13].

Stat3 has a critical function in the development of skin cancer [ 24].

Thus, it appears that PfRH5 must have a critical function in parasite survival.

All these results suggested that not only cell autonomous effects of KRAP but also particular extracellular factors would be necessary for the improved glucose tolerance in KRAP−/−-BAT and that KRAP in adipocytes would have a critical function in glucose uptake besides directly regulating insulin signaling.

Hormones have a critical function in the regulation of internal homeostasis in an organism [ 13].

These reports suggest that Tiam1 should have a critical function in the progression of epithelial cancers.

Recent results indicate that changes in cell adhesion have a critical function in tumor progression [ 11].