Subjects: A population based cohort of 318 term infants who were SGA, defined as having a birthweight less than the 15th percentile for gestational age, and without major handicap such as cerebral palsy or mental retardation, and a random control sample of 307 appropriate for gestational age (AGA) infants.
Only 9% of these 5000 individuals were false-positive SGA, with a mean SD of -1.8, and the rest had a birthweight that was truly less than – 2 SD for their gestational age.
Overall, 3,010 (12.2%) infants had a birthweight above the 90th percentile, of whom 207 (6.9%) mothers had been offered treatment for hyperglycaemia.
The boy (patient 1, Apgar score 9 10/1 10 min) had a birthweight of 2.3 kg, and the girl (patient 2, Apgar score 9 10/1 10 min) had a birthweight of 1.8 kg.
The RCTs aimed to recruit infants who were born ≤34 weeks gestation and had a birthweight of ≤1750 g.
One infant of a mother in the intervention arm had a birthweight standard deviation score below −2 (that is, below the 95% confidence interval) compared with infants of mothers in the control arm (fig 3).
Although we cannot fully exclude the possibility that tight glycaemic control contributed to fetal growth restriction, only one infant of a mother in the intervention arm had a birthweight standard deviation score below −2.
The Lifestyle-Related Factors on the Immune System and the Development of Allergies in Childhood (LISAplus) Study consists of 3,097 healthy neonates, recruited at birth, who have a birthweight >2,500 g.
By definition, SGA infants weigh ≤ 10th percentile for their gestational age; 6 of 41 (14.6%) infants in the Hg subcohort and 36 of 151 (23.8%) infants in the NNNS NICU Network Neurobehavioral Scalessubcohortort had a birthweight percentile ≤ 10%.
Thirty-six (9.8 %) of 362 singleton infants born to super-obese women had a birthweight ≥4 500 g, in contrast to 0.8%% (n = 5/608) of the singleton infants in the comparison group.
