Epidemiological and clinical studies have demonstrated that primary headache, particularly migraine, has a bidirectional relationship with depression and anxiety [1 5].
Obstructive sleep apnea (OSA) is a chronic, multisystem disorder that has a bidirectional relationship with several major neurological disorders, including Alzheimer's dementia.
Therefore, inflammation has a bidirectional role in the link between MCI, depression, and vascular pathology [ 5].
Addictive behaviors have a bidirectional relationship with pain.
Smoking has also been reported to have a bidirectional relationship with depression and may influence antidepressant response [ 22].
This is not the case in hippocampal sclerosis where longitudinal studies have suggested that the pathology can have a bidirectional relationship with seizures.
Fluid accumulation may have a bidirectional association with renal dysfunction [ 24] and may account for this rather direct relationship between heart and kidney, the cardio renal syndrome [ 24].
Thus, we could conclude that the role A has a power relation with the role B. Coordination relation: if we identify a pool/lane A has bidirectional message/sequence flows to another pool/lane B, we could assume that there is a coordination relation between A and B, as illustrated in Fig. 9.
Skating has a strong relation with architecture.
Sense, in other words, has a determinate relation with nonsense.
