Sentence examples for has RecA loading from inspiring English sources

Enzymatically, RecBCD is a DNA-dependent ATPase with powerful helicase and processive exonuclease activities, and it has RecA loading activity onto 3'-ending single-stranded DNA (ssDNA) tail for homologous DNA pairing [9], [10].

The C-terminal nuclease domain of RecB subunit (RecBnuc) is involved in the RecA loading [42].

In the case of P. syringae, RecBCD lacking RecD becomes functionally inactive, and hence the inhibitory activity of RecDPs for RecA loading on ssDNA does not arise.

Besides, the corresponding mutant RecBD1080ACD enzyme of E. coli was deficient not only in the nuclease activity but also in the RecA loading capacity [23], [25].

Additionally, the observation that LB (ΔrecB) strain expressing RecBΔnucCD enzyme, which lacks the one and all nuclease and RecA-loading domain of RecB, is proficient in the recombinogenic repair of UV-damaged DNA suggests that the mutant enzyme is probably dependent on the RecFOR function for RecA loading.

Also, SOS induction following nalidixic acid treatment requires RecBCD enzyme, which processes broken ends and facilitates RecA loading for induction of the damage response (McPartland et al. 1980).

RecF helps RecA load onto ssDNA (Friedberg et al. 2005).

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They have a loading dock.

Seminal phylogenetic studies on this superfamily by Lin et al.[ 16] proposed that: (i) bacteria contain only one recA gene, (ii) archaea contain two recA genes (RADA and RADB), (iii) yeast have four recA genes, and (iv) vertebrate animals and plants have at least seven recA genes [ 4, 5, 10, 11].

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