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'harrowing effect' is a correct and usable phrase in written English.
You can use it to describe a situation that has a distressing or disturbing effect, such as a difficult situation or an emotional experience that causes stress or suffering. For example, you could say: "The war had a harrowing effect on soldiers' mental health."
Exact(7)
This attention to detail worked to harrowing effect in Dark Elegies, Tudor's 1937 setting of Mahler's Kindertotenlieder, in which a small community mourns its dead children.
The Korean apology is satirized to harrowing effect in "At Least We Can Apologize," a darkly comic 2009 novel by the South Korean writer Lee Ki-ho, published in this country by Dalkey Archive Press as part of its Library of Korean Literature series.
But despite having this harrowing effect on his listeners, Jamie Stewart, vocalist, writer and apparent cat hugger, is really normal.
Something is drawn out of us with a harrowing effect, which Friedrich's use of color nudges toward intoxication.
The two are united only in the part of Zoe, which is taken almost intact from Boucicault's script and played straight by Amber Gray; the harrowing effect is a testament to both of the playwrights, and to the actress.
Among other Carsen productions, I particularly admired a "Frau Ohne Schatten," in Vienna, which transferred Hugo von Hofmannsthal's fairy-tale plot to the high-bourgeois salons of the Viennese fin de siècle, to unexpectedly harrowing effect.
Similar(53)
The indiscriminate nature of poison gas and the harrowing effects produced in the human body seems especially callous and inhumane.
Of course, many, many people were killed, and the War Remnants Museum in District 3 shows the harrowing effects of battle.
Photographer Lorenzo Tugnoli visited Yemen in June and again in November and December for The Washington Post, witnessing the harrowing effects of a conflict that has claimed the lives of more than 50,000 people and created one of the worst famines in history.
With its brilliant female characters and its explosive cocktail of kidnap, rape, murder and the harrowing effects of drugs on a small Yorkshire town, Happy Valley hurtled to a nerve-shredding climax on BBC1 only last month.
Considering these harrowing effects, limiting solitary confinement is not only right, it is beneficial for us all.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com