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Carefully consider the pros and cons of creating harmonized datasets and of drawing direct comparisons between similarly labelled 'groups' in different countries.
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The coordinating center then developed the harmonized dataset in cooperation with the partners.
For harmonizing datasets, it is recommended to consult a(n) (external) harmonization expert, who is familiar with Source and Target data structures.
Once early discussions of variables to be paired and harmonized between datasets had begun in the xTEND project, the development of automated tools for the generation of scripts applying discussed variable pairing and harmonization rules was undertaken so that these rules were applied in a consistent fashion that could be audited.
ORCHIDEE-GM v2.2 is integrated over Europe using the harmonized climate dataset from the ERA-WATCH reanalysis at a spatial resolution of 0.25° by 0.25° for the period 1901 2010 [49].
When merging two (or more) datasets into one common target dataset, we need to ensure that data from heterogeneous sources can be used in combination to view, query and analyse, or in short: we need to harmonize the datasets.
As each lake variable required manual interpretation and harmonizing across datasets, and thus a significant investment of time and financial resources, we prioritized the variables that were necessary to answer our initial research questions.
To address the numerous complexities of the topic of the potential impact of 5-HTTLPR variation on depression, hypothesized as a moderator of the response to stress, we have designed a coordinated meta-analysis that performs consistent, de novo analyses of all available primary data, utilizing variables that are harmonized across the datasets and with analyses that were determined a priori.
The national datasets were harmonized according to these definitions.
Many of these datasets can be harmonized to generate ecological, or area-based, indicators of socioeconomic conditions that could be incorporated in multilevel analyses.
After multi-institutional IRB approval, patient-level data was de-identified on site by the study team per HIPAA guidelines, reviewed and vetted for accuracy with clinic staff, then aggregated and harmonized to create a closed analyzable dataset.
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