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Compulsory notification of CE and harmonization of the data entry system are essential instruments for surveilling the disease in humans.
Improvements should be made in order to obtain better data, and there should be more harmonization of the data collection techniques to establish a reliable epidemiological database.
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Harmonization of the existing data will build on protocols and expertise developed in earlier collaborative EC projects (Bousquet et al. 2011; Eeftens et al. 2012; Larsen et al. 2013; Vrijheid et al. 2012; see also Supplemental Material, Previous EU projects contributing data and expertise to HELIX, pp. 2 3).
The aim of the current report is to describe the purpose of the project, the post harmonization of the cross-national data and methodological challenges related to the harmonization process The study includes data from cohort studies in five European countries (Germany, Italy, the Netherlands, Spain and the United Kingdom) on older community-dwelling persons aged ≥ 59 years.
While implementation of electronic health record (EHR) systems is rapidly occurring, the harmonization of multiple data systems and the identification of crucial information (e.g., date of diagnosis and type of diabetes) remain difficult (54).
Although the harmonization of data access agreements would facilitate data access at a global level, it should consider local legislation with respect to processing personal data and the responsibilities of data custodians, which may vary across jurisdictions.
Talking about harmonization of geographic data in the European Union, the INSPIRE directive (EC [4]) has to be mentioned.
Finally, the Directive has been seen to have serious shortcomings in the harmonization of European data protection law.
There are still challenges to solve before some technologies can be widely applied on a routine basis, including the predictive biology of indicator traits, the harmonization of data from automated systems, the motivation of farmers to record high-quality phenotypes and the genomic gap for novel traits.
The current process of manual harmonization of data sometime leaves out existing data.
An inherent requirement for data exchange is the harmonization of data formats.
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