This is achieved with the help of guidelines from the International Conference of Harmonization, International Good Clinical Practices, and companies' Standard Operating Procedures.
It is a challenge, but I am optimistic that harmonization can be achieved.
Phenotype definition and diagnosis harmonization can also be achieved through standardized clinician training, a model adopted, for example, by Finland.
The universal harmonization of MCC products might be achieved by the regulation of their molecular mass, surface roughness, and roundness.
On the other hand, harmonization of these definitions could be achieved rather easily.
Thus, taxonomic harmonization of Brachymystax can only be achieved when both genetic and morphological (especially craniological) characters of Chinese and Korean lenoks are compared to material from the Siberian range.
If harmonization of immune assays can be achieved, assays can be tested as surrogate endpoints in clinical trials, substantially accelerate the development of immunotherapeutic agents and, in addition, offer a rationale to pre-select groups of patients with high probability to benefit from subsequent immunotherapy.
Thus, our research may serve as a cautionary message to policy-makers on the limits of what can be achieved through transnational harmonization initiatives.
Apart from subject-matter specific recommendations, progress can only be achieved with further harmonization of methods, including those for environmental exposure assessment.
If international harmonization of testing approaches is to be achieved, research from China and other countries will be required to incorporate the evolving framework proposed by the NRC (2007) or the AXLR8 Consortium (2011).
