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The required format for these license applications is the Common Technical Document CTDdevelopedped by the International Council on Harmonization for use across multiple regions and most countries in the world.
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Suggestions for future harmonization activities included use of a common nomenclature and definitions, mutual recognition and reducing the number of clinical trials.
This section from a position paper published in 1997 by the International Working Group on Harmonization of Dementia Drug Guidelines [ 31] is pertinent: 'Computerized procedures currently are used extensively in general psychopharmacology, and some systems have been developed specifically for use with demented patients.
We also show results using TBSS before and after harmonization for independent validation of the proposed methodology.
In addition to centralization, harmonization across languages is beneficial for using the BelRAI portfolio in bilingual regions, so colleagues within the same hospital can complete a shared assessment in the preferred language.
The best harmonization for the prevalence estimates of dyslipidemia were achieved based on SHS (defined as drug use alone), FIRE (defined as drug use alone), and MEDSTAT (defined as ICD-10 codes E78 as secondary diagnoses).
The best harmonization for the prevalence estimates of hypertension was achieved based on SHS (defined as drug use alone), FIRE (defined as drug use alone), and MEDSTAT (defined as ICD-10 codes I10-I15 asecondaryry diagnoses).
To that end, we propose a focused conceptual approach for achieving cell harmonization that uses as a metric the spatial uniformity of the radial electric field divided by radius.
These issues highlight the need for the standardization and harmonization of methodologies used for BCR ABL quantification in Ph+ALL.
The best harmonization for the prevalence estimates of diabetes mellitus for the three different data sources was achieved using the most comprehensive definitions.
The existing Union harmonization for EU licenses supports this coordination.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com