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To replicate the modulation of such localized translation rates during heterologous expression, we used known relationships between codon usage frequencies and secondary protein structure to develop an algorithm ("codon harmonization") for identifying regions of slowly translated mRNA that are putatively associated with link/end segments.
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The goals of harmonization are to identify crucial protocol choices that influence the outcome of an applied assay, and to standardize those choices across laboratories throughout the entire field for optimal performance and consistent results.
Despite some similarities, there is no formal international harmonization for development requirements.
Data harmonization for race/ethnicity was undertaken across all seven sites.
At a regional level, the possibility of regional regulatory harmonization for health products should be pursued.
An evaluation of quality control pipelines for each platform, like the one conducted for NGS data in the SEQC study, can guide harmonization of quality control by identifying best practices.
As climate policy design moves towards domestic implementation, integration of multiple environmental objectives and international harmonization, the greatest demand is identified for new model developments at the extremes of sectoral policy assessment, through technology oriented simulation models, as well as more holistic ones (for example, integrated assessment models).
Nevertheless, without the harmonization of the conceptual framework and validation of identifying criteria, the value of the case definition standards for IEI-EMF will remain insufficient and possibly unreliable.
It can also be useful to grantees and funding administrators in suggesting potential collaborators or identifying those that share common research interests for data harmonization or other purposes.
This network is also useful to grantees and funding administrators in suggesting potential collaborators or identifying those that share common research interests for data harmonization or other purposes.
More importantly if there is to be greater harmonization of global research activities, as called for by Health Ministers in Bamako in 2008, more work will need to be done in identifying such common approaches to allow for comparable data and benchmarks to manage, organize or evaluate the global research portfolio [ 6].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com