Data standardization and harmonization across centers would promote wider dissemination and more efficient utilization of information.
These limitations are leveraged against the advantage of using large community-based cohorts of AAs for this analysis and the implementation of quality-control procedures in individual examination centers and the harmonization of imputation strategies and analytical methods.
How can the information from (a), (b), and (c) be integrated for further development of the diagnostic tools and harmonization of the diagnostic process across centers?
Serious side effects were defined in accordance with the female harmonization guidelines (Liao, 2004) and reported to the research center immediately by investigators.
The study protocol was approved by the appropriate institutional review boards/ethics committees for each center and was conducted in accordance with International Conference on Harmonization Good Clinical Practice guidelines.
The need for a larger number of pediatric HCT centers to participate in trials has resulted in a demand for harmonization of disease-specific clinical trials and immune-monitoring.
A code book (harmonization guidelines) was made explaining how the variables were harmonized (see additional file 1: Harmonization guidelines).
There should be harmonization of study designs, data collection, and analytical procedures, which may require a data coordination center that could also assess data quality and missing data.
The study was conducted in 16 centers in the UK and 8 centers in Hungary between July 2002 and February 2004 in compliance with International Conference on Harmonization guidelines, the US Code of Federal Regulations, European Community guidelines, and the Declaration of Helsinki.
This trial was conducted in compliance with the Declaration of Helsinki and with the International Conference on Harmonization Good Clinical Practice Guidelines protocol, and was approved by the Institutional Review Boards and/or Independent Ethics Committees at each of the participating investigational centers.
But "financial multipolarity" — the shifting of the center of gravity to more places, notably in the East — is making "global financial regulatory harmonization a more distant prospect than was the case before the crisis," the economists Stéphane Rottier and Nicolas Véron argued in a paper released by Bruegel this week.
