Exact(2)
In this study, the intra- and inter-batch variation of 24 target impurities suggested by the CHAMP (Collaborative Harmonisation of Methods for Profiling of Amphetamine type Stimulants) method identified in the in-house synthesized methamphetamine is discussed.
We recognize that it is often difficult to recruit sufficient healthy volunteers but the widespread availability of automated bone marker assays now means that harmonisation of methods and specific reference ranges may be possible using well-characterised populations in larger cohorts.
Similar(58)
The mission of the NORMAN network is to enhance the exchange of information and collection of data on emerging environmental substances and to encourage validation and harmonisation of measurement methods and monitoring tools so that the demands of risk assessors can be better met.
This begs the question as to whether there could be more harmonisation of the methods of health technology assessment in Europe [ 22].
This Network encourages the harmonisation of laboratory methods for the detection of influenza in EISS and assesses the quality of laboratory testing for influenza and RSV [ 25].
Other advantages of MLVA are the relative ease of implementation and harmonisation of the method between laboratories [ 17].
These controversies stress the need for further harmonisation of practices and methods of assessing the environmental risks of GMPs, in particular regarding the impact on non-target organisms [NTOs], potential long-term effects and indirect effects resulting from potential changes in agricultural management techniques.
This requires harmonisation across the centres in terms of methods used to measure exposure to a particular environmental factor of interest, which often vary from centre to centre.
Formal data pooling from registries will require harmonisation of data definitions and analytical methods.
As regards the methods validation aspects, particularly in respect of emerging pollutants, there is concern about the reliability of analytical data, due to a lack of harmonisation in method validation and QA/QC requirements.
Moreover, regarding data quality and validation, in particular with respect to emerging pollutants, the lack of harmonisation in method validation and QA/QC requirements is a cause for concern over the reliability of analytical data.
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