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Though processing mechanisms generally vary with experiment details, sharing these to the community will lead to a quicker harmonisation of approaches.
As reported in a previous paper [1], the main objective of the new commission of the Société Française des Sciences et Techniques Pharmaceutiques (SFSTP) was the harmonisation of approaches for the validation of quantitative analytical procedures.
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Only with successful implementation, can the recommendations lead to the desired changes of increased quality of care and harmonisation of approach.
This contrasts to current initiatives focusing on minimally disruptive medicine which emphasise harmonisation of treatment approaches to reduce the burden on patients with multimorbidity [ 28], possibly through development of 'synergistic' treatment models [ 29].
The early work of JECFA also brought harmonisation of the approach to safety assessment of food additives on a worldwide basis.
The advantage of using the results from the pooled analyses for risk assessment is their larger numbers and the harmonisation of the statistical approach to analyse the data, particularly the choice of cut-off points to categorize exposure [ 30].
A regional scale is believed to bring better enforcement and a harmonisation of different municipal truck access regulations.
This is analogous to the International Conference on Harmonisation (ICH) approaches.
The analysis identifies a number of design options that respond to these questions, e.g. long term contracts to ensure sufficient flexibility for statistical transfers, a coordinated, standardised joint project approach to increase transparency in the European market, and a stepwise harmonisation of joint support schemes that is based on a cost-effective accounting approach.
Based on the component paradigm for software engineering as well as on a consideration of common middleware approaches for health information systems, a generic component model has been developed supporting analysis, design, implementation and harmonisation of such complex systems.
Indeed, three-arm trials are recommended in the guidelines of the ICH (The International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use) and EMEA/CPMP (European Medicines Agency/Committee for Proprietary Medical Products) as a useful approach to the assessment of assay sensitivity and internal validation (e.g., see [ 7]).
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