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The coming decade is likely to bring enormous expansion of available health care records, and advancement of data mining and harmonisation methods.
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In this study, the intra- and inter-batch variation of 24 target impurities suggested by the CHAMP (Collaborative Harmonisation of Methods for Profiling of Amphetamine type Stimulants) method identified in the in-house synthesized methamphetamine is discussed.
We recognize that it is often difficult to recruit sufficient healthy volunteers but the widespread availability of automated bone marker assays now means that harmonisation of methods and specific reference ranges may be possible using well-characterised populations in larger cohorts.
Moreover, regarding data quality and validation, in particular with respect to emerging pollutants, the lack of harmonisation in method validation and QA/QC requirements is a cause for concern over the reliability of analytical data.
In summary, IVS was shown to be a reproducible method that benefitted from method harmonisation.
The mission of the NORMAN network is to enhance the exchange of information and collection of data on emerging environmental substances and to encourage validation and harmonisation of measurement methods and monitoring tools so that the demands of risk assessors can be better met.
This begs the question as to whether there could be more harmonisation of the methods of health technology assessment in Europe [ 22].
This Network encourages the harmonisation of laboratory methods for the detection of influenza in EISS and assesses the quality of laboratory testing for influenza and RSV [ 25].
Except for those parameters for which a consensus exists, the question of testing method harmonisation remains a very difficult issue.
Other advantages of MLVA are the relative ease of implementation and harmonisation of the method between laboratories [ 17].
However, it is obviously not sufficient just to define methods for harmonisation but this has to be reflected within the education of the staff (28, 39).
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