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Harmonic distance: let (5.7).
(iii) Harmonic distance: let (5.7) .
Then gives Harmonic distance (5.8).
In processes such as the unfolding of titin by mechanical stress, where there is an obvious force to be applied to the starting conformation, Steered MD can generate new trajectories by setting pre-defined moving harmonic distance restraints to force the system away from the starting configuration along a defined vector [9].
Secondary structural elements are maintained via extra harmonic distance restraints imposed on non-bonded beads (Table 1).
The sequence connectivity terms are upper harmonic distance restraints, with a threshold distance set to be four times the sum of the radii of the two connected beads.
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Hamming and harmonic mean distance classifiers are exploited as a mixed classifier in suggested algorithm.
Finally, MLM-KHNN proceeds in classifying the query sample to the class with the minimum harmonic mean distance.
In our method, the k nearest neighbors in each class are first found, and then used to compute k different local mean vectors, which are employed to compute their harmonic mean distance to the query sample.
To identify ancestral genes that might have been counterselected in P. carbinolicus due to close spacing of histidine codons, an index of histidine demand was computed as the number of histidine codons in a gene divided by the harmonic mean distance between them.
Open image in new window Fig. 3 The relationship between the resonance amplification factor and harmonic order, transmission distance.
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