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Unless the neuronal group has the capacity to revert to its original state given a harmful variation, in which case it is effectively behaving as a 1+1 Evolutionary Strategy [27], there is the potential that good solutions are lost.
Reducing unintended, and particularly harmful, variation is therefore a key improvement strategy.
Deliberate quality control efforts can reduce harmful variation in practice, decrease adverse events and prevent litigation [ 39- 41].
If a harmful variation is generated around the Mhc gene via the hitch-hiking effect, then it is likely to be selected against by genetic recombination.
Enrichment analysis of GO terms was performed for all the genes containing at least one harmful variation and GO terms were considered significant at FDR < 0.01.
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Darwin himself consistently refers to natural selection as a power of preserving advantageous, and eliminating harmful, variations.
The exoperidium may help to protect the maturing gleba of late-fruiting species from harmful variations in temperature or humidity, or from insect predation.
In total, 4.76 % of the harmful variations were present in CGC genes.
Among the harmful variations, the C > G substitutions are less frequent in most of the cancers.
Therefore, the presented results and pathways represent the lower boundary of harmful variations.
Inclusion of other types of genetic variations would further increase the numbers of samples containing harmful variations.
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CEO of Professional Science Editing for Scientists @ prosciediting.com