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An agent's most direct contribution to a harmful upshot of his agency is the contribution that most directly explains the harm.
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The argument developed in this article also offers an answer to the common objection that biomedical interventions have both positive and negative effects, that our brain and bodies are complex and interrelated systems so that for any intervention that seems to have a beneficial upshot, there will always be numerous negative and even harmful side effects.
Clinical trials are under way at the National Center for Complementary and Alternative Medicine, but for now the upshot is this: if you follow the directions on the packages, the products aren't considered harmful.
The upshot: pack light.
The upshot is revolutionary.
The upshot was Awakenings.
The upshot thus far?
The upshot of this "ambush"?
The upshot of all this?
What, then, is the upshot?
Upshot: the bow ties are GOING!
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com