The effect of CS on cutaneous tissue is associated not only with premature skin aging and wrinkling but also with several harmful pathologies.
Although the division of labour is highly efficient, it can lead to a number of harmful organizational pathologies; for example, units or individuals may be unable to identify and respond adequately to problems outside their competency and may approach all problems and priorities exclusively from the purview of a unit's specific capabilities.
The loss of CCL3 benefited the Sandhoff Hexb −/− mouse model, possibly because it lessened harmful microglia-associated pathology in the CNS and inhibited macrophage infiltration into the CNS.
This may lead to unnecessary and even harmful interventions, underdiagnosis of other pathology and prolonged ICU stay.
It is also unclear whether anti-dsDNA antibodies are directly pathogenic or merely correlate with pathology but do not initiate harmful responses.
Although potentially beneficial, microglial activation is most likely responsible for furthering disease pathology and DA neuron degeneration through the release of harmful substances such as pro-inflammatory cytokines, reactive oxidative species and reactive nitrogen species.
Radiographs are used to monitor thoracic kyphosis in individuals with certain pathologies (e.g. osteoporosis), exposing patients to potentially harmful radiation.
These regulatory cell populations can prevent harmful inflammation following completion of protective responses and thwart the development of autoimmune pathology.
His investigations of animals infected by pathogenic microbes and his studies of the microbial mechanisms that cause harmful physiological effects in animals made him a pioneer in the field of infectious pathology.
RAGE deficiency, however, was associated with reduced lung pathology and inflammation as well, suggesting that both HMGB1 and RAGE are harmful in the development of lung injury during the early phase of severe S. aureus pneumonia.
