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Lipid peroxidation (LP) is one of the most harmful mechanisms developed after spinal cord (SC) injury.
We hypothesized that the additive effects of cell-free Hb and hyperoxemia would result in a potentiated induction of harmful mechanisms related to cell-free hemoglobin toxicity and thereby lead to aggravated tissue damage.
Like responses to direct irradiation, bystander effects may represent a balance between protective and potentially harmful mechanisms.
Unfortunately, both the protective and harmful mechanisms induced by hypothermia vary with temperature and are poorly understood and therefore its clinical utility remains limited.
More research is required to understand the many potential beneficial and harmful mechanisms by which telehealth could affect patient reported outcomes.
Although some of the neuropathological effects of TS seem to be dependent upon nicotine-activated specific pathways [ 14], the precise cerebrovascular harmful mechanisms triggered by TS remain largely unclear.
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To counteract this harmful mechanism, the Ashwell-Morell receptor has evolved, which eliminates these modified platelets in the liver [ 35].
Moreover, UPR activation appears to depend on the reduction of protein glycosylation given that addition of GlcNAc totally prevents transformed cell death, indicating that prolonged impairment of protein folding is able to switch UPR from a protective to a harmful mechanism, especially in glucose-addicted cancer cells.
Rittirsch, D., Flierl, P. A. & Ward, M. A. Harmful molecular mechanisms in sepsis.
These include the threat of internalisation of the negative opinion of others and the employment of harmful coping mechanisms that may result in avoidance behaviours in other areas such as educational and employment opportunities.35 Such outcomes can worsen problems of ghettoization for vulnerable groups where they exist.36.
How does secondary SO4 cause mortality, if harmful biological mechanisms have not been found?
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