Exact(23)
In this context, histones are recognized as particularly harmful inflammatory mediators [3, 20, 21].
sTLR2 constitutes an important first-line negative regulatory mechanism to avoid harmful inflammatory responses [2].
The delicate process of fetal development should evidently not be disturbed by potentially harmful inflammatory responses.
Therefore, benign outcomes of influenza virus infection results from inducing sufficient IFN-mediated antiviral immunity while avoiding harmful inflammatory response.
CA results in a harmful inflammatory response and overwhelming amounts of reactive oxygen species are produced, spreading out across the body, causing leakage of vascular walls and damage to organs.
Women elicit more vigorous humoral and cell-mediated immune responses than men in response to antigenic challenges, while men have frequently been observed to exhibit more aggressive and harmful inflammatory responses to pathogens [3].
Similar(37)
These findings meant that besides direct impairments, the indirect harmful impacts (inflammatory effects) of TiO2 NPs on BBB integrity also occurred.
The protective role of AAMs in schistosomiasis was also shown to involve downregulation of harmful Th1 inflammatory responses and AAM induction was essential for survival [53].
Consequently, macrophages could provide a microenvironment to promote blastocyst growth by reducing harmful local inflammatory immune reactions.
These observations raise the possibility that chronic infections may be CHD risk factors mostly or only in these "susceptible" individuals who react to these infections with a harmful systemic inflammatory reaction, reflected in elevated levels of CRP.
Alternatively inhibition of PPARγ may promote or exacerbate a harmful pro-inflammatory response as PPARγ upregulation is known to have anti-inflammatory response (Delerive et al., 2001; Desvergne and Wahli, 1999; Devchand et al., 1996).
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