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Exact(11)
To develop a simple system to assess benefit and harm of treatment on a single scale.
Understanding short term physiological outcomes could help to better understand immediate benefits or harm of treatment.
In the sensitivity analysis, the societal perspective, including costs for carers, providers, and the harm of treatment factor, was used.
This value for the potential harm of treatment and most other parameters can be modified by the user to explore the impact on results.
However, in our analysis a more conservative estimate of one loss of life per 600 antimalarial treatments was used as the potential harm of treatment, given that use of scarce resources is already accounted for in the drug costs.
1 Choosing a cut-point is a trade-off between harm of treatment in non-cases (overtreatment) and harm of no treatment in cases (undertreatment).
Similar(49)
Once risk tools for various important outcomes and improved evidence about benefit and harm of treatments to modify these risks are available, informed decisions for providing the most appropriate care can be better supported.
Far fewer men actually die of prostate cancer, and the harms of treatment for it can include impotence and incontinence.
It allows them to live a similar length of life and avoid death from prostate cancer and avoid the harms of treatment".
This is considered ethically permissible in the context of legally incompetent minors when the proportionately greatest benefits of treatment are outweighed by the harms of treatment [6].
Often the decision is made to limit therapy (including a DNR or "do not resuscitate" order), or withdraw therapy to allow a patient to die when the harms of treatment outweigh any potential benefits.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com