Kinetic isotope effects suggest that, while in the WT, vibrational enhanced modulation of the active site contributes to the tunnel probability of HT; complexes of some of the active site mutants with the coenzyme hardly allow the relative movement of isoalloxazine and nicotinamide rings along the HT reaction.
Unfortunately, population-based studies with a long-term follow-up period could hardly allow these stratifications.
Beijing has hardly allowed the currency to budge against the dollar over the last two years as it has tried to promote its exports during the global economic and financial crisis.
Many people I encountered were amazed at the way Johnson hardly allowed that seasoned Today interviewer, John Humphrys, to get a word in edgeways, but in my view Humphrys was cleverly allowing Johnson, who sounded increasingly preposterous, to hang himself.
Falling back on the attitudes of a "poor little woman" only when it suited her, Emma Hornett, in fact, hardly allowed the menfolk in her menage to get a word in edgeways.
Southampton's high-tempo pressing game hardly allowed the visitors so much as a sniff in front of goal as Mauricio Pochettino's side secured their sixth clean sheet in nine games.
In the former case, p→ 0, 1) hardly allowing the particles to enter cristae, which gives K≈Kb = 1 for both short and long time regimes, similar to the situation discussed in [21], because Aibm≈Ab and junction density in mitochondria is much below the percolation threshold.
The dominant views on the role of network companies hardly allow us to see why this ambiguity should be there and how to deal with dilemmas, since these views are primarily monodisciplinary.
The MNT-HEPN, arguably, the most remarkable two-component system identified here, considering its dramatic overrepresentations in thermophilic archaea, is a case in point: the currently available data hardly allow one to determine whether this is a bona fide TAS or an antibiotic resistance system.
