The phrase "hard region" is correct and usable in written English.
You can use it to describe any difficult or challenging area or situation. For example, "Young entrepreneurs often find success in the hard region of the business world."
The experiments with random instances allowed us to locate the hard region for this class of problems.
Directional cell migration induced by the stiffness gradient of cell culture substrates is known as a subset of the mechanical-cue-induced taxis, so-called mechanotaxis, typically durotaxis toward hard region.
What the author shows, over and over, are the parallels between two states that are unstable, riven by worsening ethnic divisions, deeply militarised and ruled by undemocratic elites that are corrupt, murderous and cruel.This is a hard region to understand.
From analyses of trajectories of 3T3 cell movement on each prepared MEG gel, two critical criteria of the elasticity jump and the absolute elasticity to induce mechanotaxis were identified: (1) a high elasticity ratio between the hard region and the soft one, and (2) elasticity of the softer region to provide medium motility.
When tempering temperature is 823 K, the "hard regions" and "soft regions" form as a result of inhomogeneous recovery.
This ductilization strategy is based on the creation of alternating soft and hard regions via imprinting at room temperature.
In this study, alternating soft and hard regions were created in a Zr52.5Ti5Cu18Ni14.5Al10 (at%) BMG via mechanical imprinting at room temperature.
It is demonstrated that the stress concentration areas of the BMG specimens facilitate the formation of shear bands, and the presence of "soft" and "hard" regions due to the stress gradient confines the propagation.
One important class of graph-based image segmentation methods comprises interactive seed-based methods, where the user provides a partial labelling of the image by placing hard region-based constraints (known as seeds).
The West proved to be the hardest region in which to avoid hunger.
The understanding and realization of directional cell movement towards a harder region of a cell culture substrate surface, so-called mechanotaxis, might provide a solid basis for a functional artificial extracellular matrix, enabling manipulation and elucidation of cell motility.
